Author(s):
Hartati Hartati, Nangsih Sulastri Slamet, Fihrina Mohamad, Aktsar Roskiana Ahmad, Abd. Malik, Ysrafil Ysrafi, Muhammad Isrul
Email(s):
hartati.apt24@gmail.com
DOI:
10.52711/0974-360X.2026.00345 
Address:
Hartati Hartati1*, Nangsih Sulastri Slamet2, Fihrina Mohamad1, Aktsar Roskiana Ahmad3, Abd. Malik3, Ysrafil Ysrafi4, Muhammad Isrul5
1Department of Pharmacy, Poltekkes Kemenkes Gorontalo, Gorontalo Province, Indonesia.
2Department of Chemical Engineering, Politeknik Negeri Ujung Pandang, South Sulawesi Province, Indonesia.
3Faculty of Pharmacy, Universitas Muslim Indonesia, Gorontalo Province, Indonesia.
4Departement of Pharmacotherapy, Faculty of Medicine, Universitas Palangka Raya, Indonesia.
5Departement of Pharmacy, Science and Technology, Mandala Waluya University, Indonesia.
*Corresponding Author
Published In:
Volume - 19,
Issue - 6,
Year - 2026
ABSTRACT:
Diabetes Mellitus (DM) as one of the main causes of death throughout the world has increased in prevalence in several areas, one of which is South Sulawesi Province. The development of herbal medicine to overcome this continues to be carried out, one of which is through the use of the Pandan Wangi plant. Extraction and characterization of secondary metabolite compounds from the Pandan Wangi plant were carried out with the aim to analyzing the presence of active compounds that have the potential to act as antihyperglycemics. This research began with the sample extraction stage using ethanol 96% solvent, then tested for their antihyperglycemic activity in vitro using the a-glucosidase inhibitory assay method. Based on the test results, it is known that the thick ethanol extract has very active antihyperglycemic activity with an IC50 value of 5.48µg/mL. Characterization of potential secondary metabolite compounds was carried out using the GC-MS (Gas Chromatography -Mass Spectrometry) method and obtained 44 compounds that have the potential to be developed as raw materials for drugs.
Cite this article:
Hartati Hartati, Nangsih Sulastri Slamet, Fihrina Mohamad, Aktsar Roskiana Ahmad, Abd. Malik, Ysrafil Ysrafi, Muhammad Isrul. Characterization of Antihyperglycemic Compounds from Pandan Wangi (Pandanus amaryllifolius) Leaves Extract. Research Journal Pharmacy and Technology. 2026;19(6):2416-0. doi: 10.52711/0974-360X.2026.00345
Cite(Electronic):
Hartati Hartati, Nangsih Sulastri Slamet, Fihrina Mohamad, Aktsar Roskiana Ahmad, Abd. Malik, Ysrafil Ysrafi, Muhammad Isrul. Characterization of Antihyperglycemic Compounds from Pandan Wangi (Pandanus amaryllifolius) Leaves Extract. Research Journal Pharmacy and Technology. 2026;19(6):2416-0. doi: 10.52711/0974-360X.2026.00345 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-6-2
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