ABSTRACT:
The antimicrobial potential and phytochemical content of extracts from Bridelia mollis leaves, roots, and bark are investigated in this research with a view towards their exploitation as natural medicines. Against a backdrop of growing global interest in the containment of antimicrobial resistance, the research authenticates the plant-derived options with promise for broad spectrum activity against disease-causing microbes. The various plant parts were subjected to soxhlet extraction using ethanol as the solvent. Phytochemical screening and antimicrobial activity were studied against both fungi and bacteria. The phytochemical screening detected alkaloids, tannins, and saponins from all parts of the plant. Terpenoids and phenolic compounds were detected in bark and root only. The leaf and root extracts demonstrated antibacterial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Candida glabrata. These findings substantiate the folk use of Bridelia mollis in infection prevention and treatment and confirm its worth as a bioactive molecule reserve.
Cite this article:
David Mareko Boitumelo, Elizabeth Mary Mathew. In - vitro Antimicrobial Potential of Bridelia mollis Leaf, Bark and Root Extract for the Treatment of Common Bacterial and Fungal Pathogens. Research Journal Pharmacy and Technology. 2026;19(6):2444-8. doi: 10.52711/0974-360X.2026.00349
Cite(Electronic):
David Mareko Boitumelo, Elizabeth Mary Mathew. In - vitro Antimicrobial Potential of Bridelia mollis Leaf, Bark and Root Extract for the Treatment of Common Bacterial and Fungal Pathogens. Research Journal Pharmacy and Technology. 2026;19(6):2444-8. doi: 10.52711/0974-360X.2026.00349 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-6-6
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