ABSTRACT:
Neem-based facewash formulations are widely used for their potential benefits in acne management and skin health. This study aimed to evaluate the physical properties, pH, washability, Spreadability, greasiness, and antimicrobial activity of three newly developed neem facewash formulations (F1, F2, F3) compared to a marketed product. The formulations were assessed for appearance, consistency, Odor, pH, washability, and greasiness using standard protocols. Antimicrobial efficacy against Staphylococcus aureus and Candida albicans was evaluated using the disc diffusion method. All formulations exhibited a pleasant Odor and semi-solid consistency, with F1, F2, and F3 differing in colour from the green marketed product. The pH values of F1 (4.9), F2 (5.6), and F3 (5.3) were slightly lower than the marketed product (5.8), yet remained within the dermatologically acceptable range. All formulations demonstrated good washability and non-greasiness. The Spreadability of F2 closely resembled that of the marketed face wash, indicating better ease of application. Among the formulations, F2 exhibited the most significant antimicrobial activity, producing notable zones of inhibition against both S. aureus and C. albicans. In conclusion, the newly formulated neem facewashes showed favourable physical and functional characteristics, with F2 standing out due to its superior antimicrobial properties and optimal Spreadability. These findings suggest that F2 holds promise as an effective herbal skincare product. Further studies are recommended to optimize formulation parameters and assess the long-term stability, safety, and user acceptability of the formulation.