Author(s):
Jayashree Sen, Bitan Sen, Vishnupriya Thella
Email(s):
jayashree_sen@rediffmail.com
DOI:
10.52711/0974-360X.2026.00423 
Address:
Jayashree Sen1*, Bitan Sen2, Vishnupriya Thella3
1Professor, Deptt. of Anaesthesia, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
2Consultant Intensivist, Deptt of Critical Care Medicine, Artemis Hospital Gurgaon, India.
3Senior Resident, Deptt. of Anaesthesia, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 19,
Issue - 7,
Year - 2026
ABSTRACT:
Background: Total intravenous anaesthesia (TIVA) provides short-duration anaesthesia solely through the intravenous route, avoiding inhalational agents. Aim: To compare intra-operative characteristics of butorphanol versus fentanyl as co-induction agents with propofol in short duration ear, nose, throat (ENT) surgeries. Objectives: (1) Compare efficacy in analgesia and sedation. (2) Evaluate haemodynamic stability and side effects. Methods: A prospective randomized study in 60 ASA I–II patients aged 18–60 years undergoing short ENT procedures. Group B received propofol (2.5mg/kg) +butorphanol (40µg/kg) and Group F received propofol (2.5mg/kg) +fentanyl (1.5µg/kg). Analgesia, sedation, vitals, and complications were assessed. Results: Analgesic duration was longer in Group F (15.61± 2.06 min vs 6.53 ± 0.74). Sedation lasted longer in Group B (18.21 ± 3.86 min vs 5.75 ± 0.90). Haemodynamic differences were significant at 10 and 20 min. Conclusion: Fentanyl provided better haemodynamic stability and longer analgesia, whereas butorphanol produced deeper and longer sedation.
Cite this article:
Jayashree Sen, Bitan Sen, Vishnupriya Thella. Comparison of Butorphanol with Fentanyl as an Adjuvant with Propofol in Total Intravenous Anaesthesia for Short duration Surgeries in Ear Nose Throat (ENT). Research Journal of Pharmacy and Technology. 2026;19(7):2968-2. doi: 10.52711/0974-360X.2026.00423
Cite(Electronic):
Jayashree Sen, Bitan Sen, Vishnupriya Thella. Comparison of Butorphanol with Fentanyl as an Adjuvant with Propofol in Total Intravenous Anaesthesia for Short duration Surgeries in Ear Nose Throat (ENT). Research Journal of Pharmacy and Technology. 2026;19(7):2968-2. doi: 10.52711/0974-360X.2026.00423 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-7-10
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