Author(s):
Olena Ishchenko, Viktoriia Plavan, Daria Kuchynska, Virgilijus Valeika, Jolita Ostrauskaite, Igor Okhrimenko
Email(s):
dkuchinska@gmail.com
DOI:
10.52711/0974-360X.2026.00437 
Address:
Olena Ishchenko1, Viktoriia Plavan1, Daria Kuchynska1*, Virgilijus Valeika2, Jolita Ostrauskaite2, Igor Okhrimenko1
1Department of Chemical Technologies and Resource Saving, Kyiv National University of Technologies and Design, Kyiv, Ukraine.
2Department of Polymer Chemistry and Technology, Kaunas University of Technology, Kaunas, Lithuania.
*Corresponding Author
Published In:
Volume - 19,
Issue - 7,
Year - 2026
ABSTRACT:
Biopolymers, including polysaccharides, have received great attention for their such beneficial characteristics as biodegradability, lack of toxicity, safety, availability, and low cost. However, biopolymers are susceptible to microbial contamination when exposed to the external environment. A polymer blend for obtaining films from Carboxymethylated Starch (CMS) and Gelatin, with the addition of decamethoxine (DKM) as an antiseptic drug by the solution-casting method, is proposed. The effect of the DKM on changes in the properties of films has been investigated. DKM release into the aqueous phase is most intense during the first 30 min, and then the process slows down. At the same time, the complete dissolution of the films occurred after almost 4 hours. The desired rate of DKM release can be ensured by adjusting the ratio between CMS and gelatin amount in the film. The method of FTIR spectroscopy revealed that the interaction between polymers and DKM is possibly accompanied by forming a chemical bond between the oxygen atom of the carboxyl group from CMS and the nitrogen atom from DKM. The films based on CMS /Gelatin 50/50% wt. with a DKM solution`s content of 5% can be recommended for further research to develop coatings for wounds of various origins.
Cite this article:
Olena Ishchenko, Viktoriia Plavan, Daria Kuchynska, Virgilijus Valeika, Jolita Ostrauskaite, Igor Okhrimenko. Biopolymeric Materials Based on Carboxymethylated Starch. Research Journal of Pharmacy and Technology. 2026;19(7):3075-3. doi: 10.52711/0974-360X.2026.00437
Cite(Electronic):
Olena Ishchenko, Viktoriia Plavan, Daria Kuchynska, Virgilijus Valeika, Jolita Ostrauskaite, Igor Okhrimenko. Biopolymeric Materials Based on Carboxymethylated Starch. Research Journal of Pharmacy and Technology. 2026;19(7):3075-3. doi: 10.52711/0974-360X.2026.00437 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-7-24
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