Author(s):
Pushpendra Patel, Ritesh Jain, Shilpi Prasad
Email(s):
Email ID Not Available
DOI:
10.52711/0974-360X.2026.00539 
Address:
Pushpendra Patel1*, Ritesh Jain2, Shilpi Prasad3
1Research Scholar, Siddhi Vinayaka Institute of Technology and Science, Bilaspur – 495001, Chhattisgarh, India
2Professor, Dept. of Pharmacology, LCIT School of Pharmacy, Chichirda Road, Bodari, Bilaspur – 495220, Chhattisgarh, India
3Associate Professor, Dept. of Pharmaceutics, Siddhi Vinayaka Institute of Technology and Science, Bilaspur – 495001, Chhattisgarh, India
*Corresponding Author
Published In:
Volume - 19,
Issue - 8,
Year - 2026
ABSTRACT:
The present study investigated the phytochemical profile and bioactive constituents of Madhuca indica (Sapota-ceae) using comprehensive analytical techniques. Dried fruits crude drug were subjected to ethanol extraction (95% v/v) using Soxhlet apparatus, yielding high extractive values indicative of abundant secondary metabolites. Preliminary qualitative phytochemical tests confirmed the presence of flavonoids, phenols, tannins, saponins, alkaloids, steroids, and glycosides. Thin-layer chromatography (TLC) profiling of ethanol extract revealed multiple compound bands with distinct Rf values, demonstrating chemical diversity and guiding further fractionation. Gas chromatography-mass spectrometry (GC-MS) analysis identified numerous volatile and semi-volatile phytoconstituents, including long-chain fatty acids, terpenoids, and phenolic derivatives, which are often associated with antioxidant and antimicrobial properties. High-performance liquid chromatography (HPLC) fingerprinting was performed to characterize non-volatile phenolics and flavonoids, revealing major peaks at retention times consistent with known bioactive standards. Additionally, scanning electron microscopy (SEM) was used to examine the surface morphology of ethanol extract residues and prepared fractions, revealing micro-structural characteristics that correlated with crystalline and amorphous phytochemical deposits. These combined analytical approaches suggest that M. indica ethanol extracts are rich in structurally diverse phytocompounds, supporting its ethnomedicinal use and potential for development into standardized phytopharmaceutical formulations. Further studies aimed at isolating individual bioactive compounds and evaluating their pharmacological effects are warranted.
Cite this article:
Pushpendra Patel, Ritesh Jain, Shilpi Prasad. Formulation Development and Characterization of Madhuca indica Ethanolic Extract for Nutraceutical Potential. Research Journal of Pharmacy and Technology. 2026;19(8):3827-5. doi: 10.52711/0974-360X.2026.00539
Cite(Electronic):
Pushpendra Patel, Ritesh Jain, Shilpi Prasad. Formulation Development and Characterization of Madhuca indica Ethanolic Extract for Nutraceutical Potential. Research Journal of Pharmacy and Technology. 2026;19(8):3827-5. doi: 10.52711/0974-360X.2026.00539 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-8-56
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