Author(s): Safaa Hadi Hussein, Suhad Faisal Hatem Al-Mugdadi, Lec. Ali Jalil Mjali, Qabas Nather Latef, Zahraa Ahmed Okhti

Email(s): zahraaahmedokhti1981@gmail.com

DOI: 10.52711/0974-360X.2023.00016   

Address: Safaa Hadi Hussein1, Suhad Faisal Hatem Al-Mugdadi2, Lec. Ali Jalil Mjali3, Qabas Nather Latef2, Zahraa Ahmed Okhti2
1Teaching Laboratories, Medical City, Baghdad, Iraq.
2Department of Clinical Laboratories Sciences, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq.
3Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq.
*Corresponding Author

Published In:   Volume - 16,      Issue - 1,     Year - 2023


ABSTRACT:
Background: Widespread usage of antimicrobial drugs has increased the emergence of antibiotic-resistant pathogens and that's why we need new drugs. Lignin and its derivatives considered as an antioxidant, anti-inflammatory, insecticidal and antimicrobial. This study aimed to investigate the effect of lignin polymer against the bacteria isolated from clinical samples, and to study the antibiotic resistance pattern using the Vitek system. Materials and Methods: 50 clinical bacterial samples were collected from two hospitals in Baghdad city. All the isolates of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus were subjected to Vitek system to determine the resistance for 12 antibiotics. The Soda lignin polymer had been prepared from the palm tree empty fruit/ Malaysia. The biological activity of lignin polymer against resistant bacteria was evaluated by well agar diffusion method. Results: According to the Vitek system, all the bacterial isolates were multi-resistance to many antibiotics. Lignin polymer dilutions inhibited the growth of some bacterial isolates, and it was more effective in all the concentrations with a good inhibition zone on Pseudomonas aeruginosa which reached to 20mm. Conclusion: Lignin polymer has an antibacterial effect against some pathogenic multidrug resistant bacteria isolated from clinical samples, including urine and wound infection. Lignin polymer was more effective in all the concentrations on the isolates of Pseudomonas aeruginosa, with a good inhibition zone.


Cite this article:
Safaa Hadi Hussein, Suhad Faisal Hatem Al-Mugdadi, Lec. Ali Jalil Mjali, Qabas Nather Latef, Zahraa Ahmed Okhti. Antibacterial effect of Lignin Polymer on Multidrug Resistant Bacteria Identified by Vitek System. Research Journal of Pharmacy and Technology 2023; 16(1):91-6. doi: 10.52711/0974-360X.2023.00016

Cite(Electronic):
Safaa Hadi Hussein, Suhad Faisal Hatem Al-Mugdadi, Lec. Ali Jalil Mjali, Qabas Nather Latef, Zahraa Ahmed Okhti. Antibacterial effect of Lignin Polymer on Multidrug Resistant Bacteria Identified by Vitek System. Research Journal of Pharmacy and Technology 2023; 16(1):91-6. doi: 10.52711/0974-360X.2023.00016   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-1-16


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